Free NewsletterPro Login
Free Live Investors Workshop
Seats limited
Tue, Sep 29.
The dollar is losing value.
Here’s how investors can still profit.
Hosted By
Jaspreet Singh
Founder, Briefs Finance
X

Warning: Undefined variable $stocks in /var/www/briefs.co/htdocs/wp-content/plugins/oxygen/component-framework/components/classes/code-block.class.php(133) : eval()'d code on line 448

Warning: foreach() argument must be of type array|object, null given in /var/www/briefs.co/htdocs/wp-content/plugins/oxygen/component-framework/components/classes/code-block.class.php(133) : eval()'d code on line 448

Warning: Undefined variable $funds in /var/www/briefs.co/htdocs/wp-content/plugins/oxygen/component-framework/components/classes/code-block.class.php(133) : eval()'d code on line 472

Warning: foreach() argument must be of type array|object, null given in /var/www/briefs.co/htdocs/wp-content/plugins/oxygen/component-framework/components/classes/code-block.class.php(133) : eval()'d code on line 472
/* the link was here */

Adarx Raises $446.3 Million In Upsized IPO

Published Sep 25, 2026
Share:
Summary:
  • Adarx Pharmaceuticals Inc. pulled in $446.3 million by selling 26.25 million shares at $17 each.
  • The deal priced at the top of a $15 to $17 range after marketing 21.875 million shares, implying a market cap near $1.8 billion based on shares in the filings.
  • AbbVie also agreed to buy shares privately at the IPO price, targeting roughly a 4.9% stake and limited to $100 million; moreover, in May 2025, AbbVie paid Adarx $335 million upfront, with the deal leaving room for several billion more via options, milestones, and tiered royalties.

Why this IPO is getting attention

Late stage gene therapy developers do not come public every day, and Adarx is leaning into that moment. The San Diego company priced at the high end and upsized the offering, a sign of solid demand for its siRNA pitch. With fresh cash, a big pharma partner and multiple programs running, investors get a clearer read on where this pipeline could head next.

Deal terms and shifting stakes

Adarx sold 26.25 million shares at $17, as disclosed Thursday, after marketing 21.875 million shares in the $15 to $17 range. Using the outstanding share count in regulatory filings, that price implies an equity value of about $1.8 billion.

Ownership will move around post-listing. OrbiMed Advisors, a backer, is set to hold about 23% following the IPO versus 31% before. LAV is expected at 12% compared with 16%, Chief Executive Officer Zhen Li at 10% down from 13%, and SR One at 8.2% from 11%.

Big financial events may grab attention, but steady habits protect and grow your wealth. Join Briefs Finance CEO Jaspreet Singh on September 29th for a FREE live investor workshop, How to Profit From A Dollar That's Losing its Value, where he shows how we're spotting investment opportunities as the dollar falls. Save your spot.

Partners, funding and banks behind the deal

AbbVie Inc., already collaborating with Adarx, arranged to participate through a separate purchase at the IPO price that targets roughly a 4.9% position, with that buy limited to no more than $100 million. Under the collaboration, Adarx received $335 million upfront in May 2025 and could see several billion dollars in further consideration through option fees, development and commercial milestones, plus tiered royalties.

On the private side, Bain Capital Life Sciences and TCGX spearheaded a $200 million Series C round in 2023 that added BlackRock Inc., Invus, Marshall Wace and T. Rowe Price Group Inc. as first-time investors. The IPO was led by JPMorgan Chase & Co., Morgan Stanley, Toronto-Dominion Bank, UBS Group AG and LifeSci Capital.

What Adarx makes and what the numbers say

Adarx develops small interfering ribonucleic acid therapies aimed at diseases of the eye and kidney, as well as obesity and Alzheimer's. The appeal is precision at the genetic target level without making permanent edits to a person's DNA. Three candidates are already being tested in humans and two more are in preclinical work.

The company expects trading to begin Friday on the Nasdaq Global Market under the ticker ADRX.

Keeping a long term perspective helps you preserve gains and pursue future opportunity. Our CEO Jaspreet Singh is hosting a FREE live investor workshop, How to Profit From A Dollar That's Losing its Value, on September 29th. Sign up free to join him live.

Disclosure

Recent News

1 2 3 … 85

Get Market Briefs delivered to your inbox every morning for free!

No fluff. No noise. No politics. Just finance news you can read in 5 minutes.

Blogs

September 25, 2026
BRIEFS EXCLUSIVE: 43% Of Respondents Say Bills Outran Their Income Over Past Two Years
  • 43% of the 494 Market Briefs readers surveyed said their bills grew faster than their income over the past two years, even though 79% could cover a surprise $5,000 expense tomorrow.
  • Half of readers own gold or crypto, the two classic bets against a weaker dollar, and only 13% bought nothing at all in the last 12 months.
  • The median reader says it takes $150,000 a year to feel financially secure, about $62,000 above the U.S. median household income.
Read More
September 24, 2026
The 2026 Economic Reset Is Starting: Are We in a Recession, or Is the Pain Still Ahead?
  • The Federal Reserve has flipped from stimulating the economy to fighting inflation with higher interest rates, while the White House still wants growth at almost any cost.
  • The national debt tops $40 trillion, has outgrown the entire U.S. economy, and its interest payments are now the government's fastest-growing expense.
  • Higher rates bring pain for private equity, private credit, and speculative assets, but they open opportunities for investors holding cash, treasuries, and value assets.
Read More
September 23, 2026
Are We in a Recession? Without AI, America Might Already Be in One - and Washington Knows It
  • The White House attributes about three quarters of U.S. economic growth to AI, and many believe the economy would already be in a recession without it.
  • Washington has three reasons it cannot let the AI boom slow down: staying the world's superpower, outgrowing $40 trillion in national debt, and protecting a government stock portfolio worth billions.
  • Every market goes through booms and busts, and investors who understand the cycle get to buy the downturn instead of panic-selling with the crowd.
Read More
September 22, 2026
Will Interest Rates Go Down in 2026? Where the Money Moves Either Way
  • The Fed is leaning toward higher rates to fight 4% inflation, while the White House and a cracking job market push the other way.
  • If rates rise, money has tended to move toward short-term Treasuries, floating-rate loans, energy, banks and dividend payers.
  • If rates fall, it has tended to move toward gold, silver and Bitcoin, real estate, small caps, the S&P 500 and speculative bets.
Read More
September 21, 2026
How the Federal Reserve Makes Money - and Why It Just Posted Its Biggest Loss Ever
  • For 109 years the Federal Reserve created money, lent it to the U.S. government and handed the interest it collected back to Washington - almost $1 trillion in the decade starting in 2011.
  • Pandemic-era lending locked the Fed into earning about 2% on trillions of dollars while it now pays banks around 4%, producing a record loss of hundreds of billions in 2026.
  • The Fed covers its losses by creating money and the government covers its lost revenue by borrowing, and both feed the inflation that eats at the dollars in your account.
Read More
September 18, 2026
Kevin Warsh Just Defied Trump: What the Fed Rate Hike Means for Your Money
  • The Fed raised rates for the first time since 2023 in a unanimous vote led by Kevin Warsh, the chairman President Trump appointed to cut them.
  • Higher rates make the $40 trillion national debt, business loan resets and mortgages more expensive, but they strengthen the dollar and pay investors holding cash.
  • The war with Iran is pushing up oil, grocery and chip prices, another hike is likely in 2026, and recession talk is about to get louder.
Read More
September 17, 2026
Why America Bailed Out the Yen: The Japan Carry Trade, the Dollar and Your Mortgage Rate
  • In July 2026 the US sent money to steady the yen because Japan is the largest foreign owner of US debt, and Washington needs Japan to keep lending.
  • For decades the Japan carry trade let Wall Street borrow yen at essentially 0% and pour it into US stocks, real estate and Treasuries, and rising Japanese rates are shutting that off.
  • A weaker yen means fewer buyers for the dollar and for US debt, which pushes Treasury rates up and drags mortgage, car loan and credit card rates up with them.
Read More
September 16, 2026
Treasury Yields Are Spiking Because Lenders Are Backing Away From U.S. Debt
  • The U.S. is paying its highest 30-year borrowing rate in about two decades because its biggest lenders, the Fed, foreign governments, and banks, are all pulling back from Treasuries.
  • Every mortgage, car loan, credit card, and business loan is priced off the 10-year Treasury yield, so when Washington pays more to borrow, so do you.
  • With about $40 trillion of debt against a $32 trillion economy, the country either outgrows its debt or slides into a doom loop, and investors need a plan for both.
Read More
September 15, 2026
Fiat Currency Runs on Trust, and the World Just Stopped Trusting the Dollar
  • Gold has overtaken US treasuries as the world's top reserve asset, and central banks are now buying less US debt and more gold.
  • The US dollar is a fiat currency, meaning it's backed by a promise rather than gold, so it loses value when fewer countries want to hold it.
  • Whether the US economy or its national debt grows faster from here decides which assets stand to benefit next.
Read More
September 14, 2026
Why RAM Prices Are Soaring - and Where the Money Is Moving
  • Memory chips - the RAM inside phones, laptops, fridges, and trucks - are in a shortage Tim Cook called a 100-year flood, and some memory prices have climbed about 90% in a single quarter.
  • Four forces hit at once: AI demand, a production shutdown in 2023, build times that push any fix to 2028 at the earliest, and a bombed helium plant in Qatar.
  • The last two supply shocks ended in aggressive Fed rate hikes and market drops of around 45% and 20%, and this time Washington is spending heavily to bring memory production home.
Read More
1 2 3 … 27
Share via
Copy link